Anti-Human Mesothelin Recombinant Antibody (TAB-201)
CAT#: TAB-201
Recombinant monoclonal antibody to Mesothelin. It is a chimeric monoclonal antibody designed for the treatment of cancer.
Tested Data
Gene Expression
WB
Figure 1 Anti-MSLN Antibody (TAB-201) in WB
Western blot analysis of TAB-201 was performed with Human MSLN Protein.
ELISA
Figure 2 Anti-MSLN Antibody (TAB-201) in ELISA
ELISA analysis of TAB-201 was performed by coating with Human MSLN Protein.
DB
Figure 3 Anti-MSLN Antibody (TAB-201) in Dot Blot
Dot Blot analysis of TAB-201 was performed by coating with Human MSLN Protein.
SDS-PAGE
Figure 4 Anti-Human Mesothelin Recombinant Antibody (TAB-201) in SDS-PAGE
SDS-PAGE analysis of TAB-201 in non-reduced (line 1) and reduced (line 2) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result of different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively.
SEC-HPLC
Figure 5 Anti-Human Mesothelin Recombinant Antibody (TAB-201) in HPLC
The purity of this antibody is> 95% as determined by SEC-HPLC.
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Subcellular Location
Figure 1 IF staining of human cell line HeLa
Immunofluorescent staining of human cell line HeLa shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17172/1276_A4_4_selected.jpg
Normal Tissue
Figure 2 Fallopian tube
Ciliated cells (cilia axoneme)
Staining:
High
Intensity: Strong
Ciliated cells (tip of cilia)
Staining:
High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2216/6076_A_7_7.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (CAPAN-2, EFO-21, HeLa, hTCEpi, OE19)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000102854-MSLN
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Specifications
- Immunogen
- Spleen lymphocytes from mice fused with OVCAR-3, an ovarian tumorcell line derived from poorly differentiated adenocarcinoma of the ovary.
- Host Species
- Mouse
- Derivation
- Chimeric (mouse/human)
- Type
- IgG1 - kappa
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
- Related Disease
- Pancreatic cancers
Product Property
- Purity
- Purity >95% by SDS-PAGE.
- Storage
- Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Target
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-201, RRID: AB_3111870)
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Biosimilar Overview
Please refer to Amatuximab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Amatuximab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-009 | Recombinant Anti-human MSLN VHH Single Domain Antibody | WB, IHC, FC, FuncS | Llama VHH |
| HPAB-M0391-YC | Recombinant Llama Anti-MSLN Single Domain Antibody (HPAB-M0391-YC) | ELISA, FC, IF | Llama VHH |
| HPAB-M0392-YC | Recombinant Llama Anti-MSLN Single Domain Antibody (HPAB-M0392-YC) | ELISA, FC, IF | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G052E | Anti-MSLN immunotoxin RG7787 (Fab)-PE | Cytotoxicity assay, Function study | |
| AGTO-G053E | Anti-Msln immunotoxin (IgG)-PE | Cytotoxicity assay, Function study | |
| AGTO-L035E | anti-MSLN immunotoxin K1 (IgG)-PE | Cytotoxicity assay, Functional assay | |
| AGTO-L063E | anti-MSLN immunotoxin 8B35 (scFv)-PE | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0833CL | Human Anti-MSLN Recombinant Antibody (TAB-0833CL) | ELISA, FuncS, Activ, FC | Human IgG1 |
| TAB-0834CL | Human Anti-MSLN Recombinant Antibody (TAB-0834CL) | ELISA, FuncS, FC, SPR, Inhib | Human IgG1, κ |
| TAB-0835CL | Human Anti-MSLN Recombinant Antibody (TAB-0835CL) | ELISA, FC, FACS, Inhib | Human IgG1, λ |
| TAB-0833CL-S(P) | Human Anti-MSLN Recombinant Antibody; scFv Fragment (TAB-0833CL-S(P)) | ELISA, FC | Human scFv |
| TAB-0834CL-S(P) | Human Anti-MSLN Recombinant Antibody; scFv Fragment (TAB-0834CL-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0376MZ | Chicken Anti-MSLN Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2302 | Hi-Affi™ Recombinant Rabbit Anti-MSLN Monoclonal Antibody (DS2302AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0041-CN | Mouse Anti-MSLN Recombinant Antibody (HPAB-0041-CN) | FC, WB, ELISA | Mouse IgG |
| HPAB-0042-CN | Mouse Anti-MSLN Recombinant Antibody (HPAB-0042-CN) | FC, WB, ELISA | Mouse IgG |
| HPAB-0043-CN | Mouse Anti-MSLN Recombinant Antibody (HPAB-0043-CN) | FC, WB, ELISA | Mouse IgG |
| HPAB-0044-CN | Human Anti-MSLN Recombinant Antibody (HPAB-0044-CN) | FC, WB, ELISA | Human IgG |
| HPAB-0045-CN | Human Anti-MSLN Recombinant Antibody (HPAB-0045-CN) | FC, WB, ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0442LY-S(P) | Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0442LY-S(P)) | ELISA, FC, IHC, WB | Human scfv |
| HPAB-0443LY-S(P) | Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0443LY-S(P)) | ELISA, FC, IHC, WB | Human scfv |
| HPAB-0444LY-S(P) | Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0444LY-S(P)) | ELISA, FC, IHC, WB | Human scfv |
| HPAB-M0155-YC-S(P) | Human Anti-MSLN Recombinant Antibody (clone M/YC-16); scFv Fragment | ELISA, WB | Mouse scFv |
| HPAB-M0157-YC-S(P) | Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-M0157-YC-S(P)) | FuncS | Rabbit scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-201 | Afuco™ Anti-MSLN ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-201) | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0101 | APC-H-2Db/Human Mesothelin (GQKMNAQAI) MHC Tetramer | FCM | |
| MHC-CN0102 | PE-H-2Db/Human Mesothelin (GQKMNAQAI) MHC Tetramer | FCM | |
| MHC-CN1049 | PE-A*01:01/Human MSLN (TLDTLTAFY) MHC Tetramer | FCM, IHC | |
| MHC-YF238 | A*02:01/Human Mesothelin (SLLFLLFSL) MHC Monomer | MHC Multimer | |
| MHC-YF239 | A*02:01/Human Mesothelin (VLPLTVAEV) MHC Monomer | MHC Multimer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0884-FY-S(P) | Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0884-FY-S(P)) | FC, IHC, ELISA | Mouse scFv |
| HPAB-0885-FY-S(P) | Human Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0885-FY-S(P)) | FC, IHC, ELISA | Human scFv |
| HPAB-0886-FY-S(P) | Mouse Anti-MSLN Recombinant Antibody; scFv Fragment (HPAB-0886-FY-S(P)) | FC | Mouse scFv |
| HPAB-2735LY-F(E) | Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-2735LY-F(E)) | ELISA, FC | Human Fab |
| HPAB-2736LY-F(E) | Human Anti-MSLN Recombinant Antibody; Fab Fragment (HPAB-2736LY-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY69 | Human Anti-MSLN (clone SS) scFv-Fc Chimera | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC539 | Recombinant Anti-MSLN Vesicular Antibody, EV Displayed (VS-0425-YC539) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4533 | Anti-MSLN Immunohistochemistry Kit | IHC | |
| VS-0525-XY4534 | Anti-Mouse MSLN Immunohistochemistry Kit | IHC | |
| VS-0525-XY4535 | Anti-Rat MSLN Immunohistochemistry Kit | IHC |
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